However, it may be associated with an increased risk of developing cancer. Only a few people with GERD develop Barrett’s Esophagus. It is a long-term complication of Gastroesophageal Reflux Disease (GERD). The cells change from squamous type skin cells like the ones on our skin, to cells similar to the lining of the intestinal (gut) surface. When the normal tissue lining the esophagus (the tube that connects the mouth to the stomach) changes to tissue that more resembles the intestinal lining instead of the typical appearance of the esophageal lining, it is called Barrett’s Esophagus. Barrett’s esophagus, or “Barrett’s type changes” of the esophagus describe an abnormal condition which changes the cell type of the esophageal lining and increases the chances of esophageal cancer.
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